When you set out on a journey along the Mississippi River, you’re stepping into one of the most iconic landscapes in the United States. This legendary waterway stretches 2,300 miles, from Minnesota down to Louisiana, winding past cities, small towns, and untouched nature that tell the story of America’s heartland.
So if you’re dreaming of a cruise that combines relaxation with discovery, here are some of the best destinations to explore along the Mississippi River as you follow its winding path from north to south.
St. Paul, Minnesota
In St. Paul, marvel at the seamless blend of urban sophistication and historical charm. This vibrant city invites you to explore its well-preserved Victorian architecture and bustling local markets. The Science Museum of Minnesota offers an intriguing look into the natural world, perfect for inquisitive minds.
Stroll along the riverfront and witness the Mississippi’s grand beginning, where its waters start their journey southward. A visit to St. Paul wouldn’t be complete without exploring its dynamic arts scene, where theaters and galleries abound.
La Crosse, Wisconsin
Nestled amidst picturesque bluffs, La Crosse offers stunning vistas that captivate the soul. The city’s landscape is a masterpiece painted by nature, where the river’s calm waters reflect the sky’s changing colors.
La Crosse’s historic downtown is a treasure trove of shops and eateries, each offering a taste of local flavor. The annual Oktoberfest adds a dash of Bavarian flair, drawing visitors from all corners.
Dubuque, Iowa
Dubuque stands as a testament to the river’s influence on America’s development. The city’s rich history is woven into its architecture, with landmarks like the Shot Tower narrating tales of yesteryears.
The National Mississippi River Museum & Aquarium brings the river’s ecosystem to life, offering a glimpse into the diverse habitats along its banks. Enjoy a ride on the Fenelon Place Elevator for panoramic views that stretch for miles.
Davenport, Iowa
In Davenport, art and innovation converge along the river’s edge. The Figge Art Museum houses a collection that spans continents and centuries, offering a global perspective in a Midwestern setting.
The city’s riverfront is a hub of activity, with miles of trails that invite you to bike or walk alongside the flowing waters. Davenport’s vibrant music scene adds rhythm to the air, especially during the annual Bix Beiderbecke Memorial Jazz Festival.
Hannibal, Missouri
In Hannibal, literary history intertwines with rustic beauty. The boyhood home of Mark Twain stands as a tribute to the legendary author, drawing fans from around the world.
The Mississippi River here serves as a backdrop to countless stories, with steamboat cruises offering a step back in time. Explore the Mark Twain Cave, where adventure awaits beneath the earth’s surface, echoing the tales of Tom Sawyer and Huck Finn.
St. Louis, Missouri
St. Louis, a city with a spirit as mighty as the river it borders, welcomes visitors with open arms. The iconic Gateway Arch stands as a beacon of exploration, inviting you to ponder the city’s pivotal role in westward expansion.
Venture into the vibrant neighborhoods filled with eclectic eateries and live music venues. The Missouri Botanical Garden offers a serene escape, where nature thrives alongside urban energy.
Memphis, Tennessee
In Memphis, the soul of music reverberates through every street. Beale Street is the heartbeat of the city’s music scene, where blues and rock ‘n’ roll legends were born.
The Mississippi River adds a harmonious backdrop, its rhythm ever-present in Memphis’s cultural tapestry. Delve into the city’s storied past at the National Civil Rights Museum, located at the historic Lorraine Motel.
Vicksburg, Mississippi
Vicksburg is a place where history lives on, its past etched into the landscape. The Vicksburg National Military Park stands as a solemn reminder of the pivotal Civil War battles fought here.
The river’s presence is felt deeply, shaping the town’s history and future. Explore the charming streets lined with antebellum homes, each telling its own story of resilience and change.
Natchez, Mississippi
Natchez exudes Southern charm, its antebellum architecture a testament to a bygone era. The city’s grand homes are adorned with intricate details, offering a glimpse into the opulence of the past.
The Mississippi River flows quietly alongside, a silent witness to centuries of history. Discover the local culture through its vibrant festivals, where music and tradition blend seamlessly.
Baton Rouge, Louisiana
Baton Rouge, with its rich tapestry of culture and politics, is a city of contrasts. The Louisiana State Capitol stands tall, a beacon of the state’s vibrant spirit.
The city’s culinary scene is a feast for the senses, offering flavors that reflect its diverse heritage. The Mississippi River winds its way through Baton Rouge, a constant companion to its dynamic energy.